Keith,adefeatedadultstoreowner,fallsforayoungerwomanwhovisitshisshoplookingforagift.Whentheirrelationshipturnsphysical,Keith’sfailuretoperformleadshimtoastrangedoctorwhooffershopeintheformofanewexperimentaldrug.TheexperiencegivesKeithmuchmorethanrenewedmanhood.ItalsoprovidesaglimpseintoaparalleluniversewhereheisnotonlythesingerofthebandOFF!,butalsothetargetofanevilalienspeciesthatwillstopatnothingtopreventthegroupfrommakinganewalbumwhichholdsthekeytoanawakeningofhumanconsciousness.
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